Prevalence, prescription patterns, and quality of life of anaemia in adults with chronic renal disease

Akkam Sandeep
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Karthikeyan Elumalai
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Helen Williams
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Sunilkumar Salkapuram
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Shanmugam Anandakumar
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Sivaneswari Srinivasan
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Department of Postgraduate Research in Clinical Pharmacy, Santhiram College of Pharmacy, India
Department of Pharmaceutical Chemistry, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, Tamilnadu, India
Faculty of Pharmacy, Bharath Institute of Higher Education and Research, India
Department of Postgraduate Research in Clinical Pharmacy, Santhiram College of Pharmacy, India
Department of Microbiology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Tamil Nadu, India
Department of Pharmaceutics, KK College of Pharmacy, India
Received: 31 July 2023 / Revised: 1 September 2023 / Accepted: 9 September 2023 / Published: 30 December 2023

Abstract

Introduction and aim. Anaemia is a chronic kidney disease (CKD) condition characterised by a decline in glomerular filtration rate (GFR) and impaired kidney function. The aim of this study was to assess the prevalence, prescribing patterns, and quality of life of anaemia in patients with chronic renal disease who were adults (>18 years of age) at a tertiary care hospital.

Material and methods. Data on demographic characteristics, laboratory results, medication prescriptions, and quality of life assessments were collected. Statistical tests were performed to determine associations between anaemia prevalence and factors like age, gender, and CKD stage. The study included 132 patients, with a gender distribution of 89 men and 43 women.

Results. The most frequently prescribed drugs are epoetin (15.06%), multivitamins (14.82%), iron (10.65%), folic acid (10.22%), calcium carbonate (8.17%), calcitriol (5.6%), and omeprazole (4.22%). The cardiovascular system, blood disorders, and blood-producing organs come after the gastrointestinal tract and metabolism in the first anatomical level of the ATC classification.

Conclusion. It suggests hospital audits and recommendations for improved prescription practices. Further investigation into anaemia causes and drug class appropriateness is needed, and implementing improvements could potentially improve health outcomes.

 

Cite

Sandeep A, Elumalai K, Williams H, Salkapuram S, Anandakumar S, Srinivasan S. Prevalence, prescription patterns, and quality of life of anaemia in adults with chronic renal disease. Eur J Clin Exp Med. 2023;21(4):785–792. doi: 10.15584/ejcem.2023.4.20.

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