Neoadjuvant therapy in breast cancer - objectives and tasks

Elżbieta Ostańska
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Dorota Bartusik-Aebisher
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David Aebisher
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Ewa Kaznowska
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Clinical Department of Pathomorphology, Clinical Hospital No. 1 in Rzeszow, Rzeszow, Poland
Department of Biochemistry and General Chemistry, Medical College of the University of Rzeszow, University of Rzeszow, Rzeszow, Poland
Department of Photomedicine and Physical Chemistry, Medical College of Rzeszów University, Rzeszów, Poland
Department of Morphological Sciences, Institute of Medical Sciences, Medical College of Rzeszow University, Rzeszow, Poland
Received: 12 October 2018 / Accepted: 29 October 2018 / Published: 30 June 2019

Abstract

Introduction. Neoadiuvant therapy (NCT) in the treatment of breast cancer is employed for patients with early stage disease or with inoperable disease. NCT can decrease the tumor volume. It can facilitate breast conservation therapy. Response to NCT is a strong predictor of outcome breast cancer (BC). Direct target therapies has markedly improved the result of treatment BC.

Aim. Therapy for breast cancer continues to improve. The importance of tumor burden on local control rates will be in the future.

Material and methods. This analysis was performed using a systematic literature search.

Results. The latest scientific reports give hope for greater safety and a better life for patients based on optimized and effective therapy.

Conclusion. Currently, improving the effectiveness of breast cancer treatment is mainly related to the optimal use of classic therapeutic strategies. New classes of substances have been approved for treatment or are in advanced stages of clinical development.

 

Cite

Ostańska E, Bartusik-Aebisher D, Aebisher D, Kaznowska E. Neoadjuvant therapy in breast cancer – objectives and tasks. Eur J Clin Exp Med. 2019;17(2):153–156. doi: 10.15584/ejcem.2019.2.8

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