New endoscopic treatment methods for PPI-resistant GERD

Barbara Sosna
Dorota Bartusik-Aebisher
ID
Email src
Grzegorz Cieślar
ID
Aleksandra Kawczyk-Krupka
ID
Email src
Wojciech Latos
School of Medicine with the Division of Dentistry in Zabrze, Department of Internal Diseases, Angiology and Physical Medicine, Center for Laser Diagnostics and Therapy, Medical University of Silesia in Katowice, Bytom, Poland
Department of Biochemistry and General Chemistry, Medical College of the University of Rzeszow, University of Rzeszow, Rzeszow, Poland
Department of Internal Medicine, Angiology and Physical Medicine, Centre for Laser Diagnostics and Therapy, Medical University of Silesia in Katowice, Bytom, Poland
Department of Internal Medicine, Angiology and Physical Medicine, Centre for Laser Diagnostics and Therapy, Medical University of Silesia in Katowice, Bytom, Poland
Department of Internal Medicine, Angiology and Physical Medicine, Centre for Laser Diagnostics and Therapy, Medical University of Silesia in Katowice, Bytom, Poland
Received: 20 June 2021 / Revised: 09 July 2021 / Accepted: 19 July 2021 / Published: 30 December 2021

Abstract

Introduction. Gastroesophageal reflux disease (GERD) is a common disease with the highest prevalence in North America. Up to 40% of patients report persistent gastroesophageal reflux disease (GERD) symptoms despite proton pump inhibitor (PPI) therapy.

Aim. The aim of this article is to complete discuss the GERD characterized by heartburn and/or regurgitation symptoms.

Material and methods. We discuss here the evidence for medical therapy for PPI nonresponsive GERD.

Analysis of the literature. GERD may present with a variety of other symptoms, including water brash, chest pain or discomfort, dysphagia, belching, epigastric pain, nausea, and bloating. In addition, patients may experience extraesophageal symptoms like cough, hoarseness, throat clearing, throat pain or burning, wheezing, and sleep disturbances.

Conclusion. There has been an increase in GERD prevalence. GERD is one of the most common gastrointestinal disorders managed by gastroenterologists and primary care physicians.

 

Cite

Sosna B, Bartusik-Aebisher D, Cieślar G, Kawczyk-Krupka A, Latos W. New endoscopic treatment methods for PPI-resistant GERD. Eur J Clin Exp Med. 2021;19(4):322–325. doi: 10.15584/ejcem.2021.4.6

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited