Malignant lymphoma or Kikuchi-Fujimoto disease – case report

Karolina Syrek-Kaplita
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Bożenna Karczmarek-Borowska
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Agata Sałek
Ludmiła Fudali
Clinic of Clinical Oncology, Podkarpackie Oncology Center, Clinical Provincial Hospital No. 1 in Rzeszow, Poland
Clinic of Clinical Oncology, Podkarpackie Oncology Center, Clinical Provincial Hospital No. 1 in Rzeszow, Poland
Clinic of Clinical Oncology, Podkarpackie Oncology Center, Clinical Provincial Hospital No. 1 in Rzeszow, Poland
Zakład Patomorfologii Wojewódzkiego Szpitala Specjalistycznego w Rzeszowie, Polska

Abstract

The case is a 70-year-old female patient, who was directed to the Oncology Center with suspected malignant lymphoma. The evaluation and histopathological reexamination suggested Kikuchi-Fujimoto disease. The patient was then referred to a Rheumatology Clinic. The Kikuchi-Fujimoto disease or histiocytic, necrotizing lymphadenitis without granulocytic infiltration is a lymphadenopathy of unknown etiology. It was first described in Japan by independent researchers Kikuchi and Fujimoto in 1972. During the diagnostic workup infectious, autoimmune, or neoplastic diseases are taken into consideration. The diagnosis is confirmed both by clinical and histopathological features of the disease. Symptomatic treatment is administered, but the changes regress spontaneously in most cases.

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