Lycopene activity on lung and kidney cancer cells by T2 relaxation time 1H Magnetic Resonance Imaging in vitro

Katarzyna Pogoda
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Maria Pucka
Jacek Tabarkiewicz
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Zuzanna Bober
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David Aebisher
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Sabina Galiniak
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Dorota Bartusik-Aebisher
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Centre for Innovative Research in Medical and Natural Sciences, Medical College of University of Rzeszów, Rzeszów, Poland
Centre for Innovative Research in Medical and Natural Sciences, Medical College of University of Rzeszów, Rzeszów, Poland
Department of Human Immunology, Institute of Medical Sciences, Medical College, University of Rzeszow, Rzeszow, Poland
Department of Photomedicine and Physical Chemistry, Medical College of University of Rzeszów, Rzeszów, Poland
Department of Photomedicine and Physical Chemistry, Medical College of Rzeszów University, Rzeszów, Poland
Department of Biochemistry and General Chemistry Medical College of Rzeszów University, Rzeszów, Poland
Department of Biochemistry and General Chemistry, Medical College of the University of Rzeszow, University of Rzeszow, Rzeszow, Poland
Received: 20 November 2019 / Accepted: 23 January 2020 / Published: 30 March 2020

Abstract

Introduction. The paper presents the results of a study of cell cultures of lung cancer and kidney cancer using lycopene performed using clinical magnetic resonance imaging.

Aim. The aim of the study was to evaluate lycopene activity on tumor cell cultures.

Material and methods. For this purpose, MR tests were performed using the technique of determining transverse relaxation.

Results. Described here studies demonstrated that lycopene may inhibit the growth of A549 and ACHN cell lines.

Conclusion. We determine changes in spin lattice relaxavity T2 to monitor treatment of lung cancer cell line A549 and kidney cancer cell line ACHN cells treatment with lycopene. 

 

Cite

Pogoda K, Pucka M, Tabarkiewicz J et al. Lycopene activity on lung and kidney cancer cells by T2 relaxation time 1 H Magnetic Resonance Imaging in vitro. Eur J Clin Exp Med. 2020;18(1):5–9. doi: 10.15584/ejcem.2020.1.1

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