Arterial stiffness can predict cardiorespiratory fitness in type 2 diabetic patients?

Clara Italiano Monteiro
ID
Rodrigo Polaquini Simões
Alessandro Domingues Heubel
Claudio Donisete da Silva
ID
Paula Angélica Ricci
ID
Ariane Petronilho
Audrey Borghi-Silva
ID
Renata Gonçalves Mendes
ID
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Cardiopulmonary Physiotherapy Laboratory, Department of Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil
Physiotherapy Department, Federal University of Sao Carlos, São Carlos, São Paulo, Brazil
Physiotherapy Department, Federal University of Sao Carlos, São Carlos, São Paulo, Brazil
Cardiopulmonary Physiotherapy Laboratory, Department of Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil
Cardiopulmonary Physiotherapy Laboratory, Department of Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil
Physiotherapy Department, Federal University of Sao Carlos, São Carlos, São Paulo, Brazil
Cardiopulmonary Physiotherapy Laboratory, Department of Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil
Cardiopulmonary Physiotherapy Laboratory, Department of Physical Therapy, Federal University of Sao Carlos, Sao Carlos, Sao Paulo, Brazil
Received: 1 November 2021 / Revised: 8 December 2021 / Accepted: 11 December 2021 / Published: 30 March 2022

Abstract

Introduction and aim. Arterial stiffness (AS) has been associated with reduced cardiorespiratory fitness (CRF). The aim of this study was to verify if there is a relationship between augmentations index (AIx), as an index for AS assessment, and CRF in individuals with type 2 Diabetes Mellitus (T2DM).

Material and methods. Observational cross-sectional study including 32 individuals diagnosed with T2DM who performed two evaluations: 1. Arterial stiffness assessment using SphygmoCor and 2. CRF throughout a cardiopulmonary exercise test on a treadmill ergometer. Oxycon Mobile® device was used to obtain oxygen uptake consumption at peak (V˙O2peak); oxygen uptake efficiency slope (OUES) determined by linear regression in reason of the logarithmic transformation of the ventilation and V˙O2 obtained every minute of exercise test. Statistical analysis comprised Pearson’s Correlation and linear regression analysis performed in SigmaPlot.

Results. There was a significant correlation between AS and CRF: AIx and OUES; AIx@75 and; OUES. In linear regression, AIx was determinant for V˙O2peak and OUES – AIx and; AIx@75 and V˙O2peak.

Conclusion. AS was associated with CRF in individuals with T2DM. These results contribute to the body of evidence linking arterial functional properties to CRF and suggests greater attention for this important index.

 

Cite

Monteiro CI, Simões RP, Heubel AD, et al. Arterial stiffness can predict cardiorespiratory fitness in type 2 diabetic patients? Eur J Clin Exp Med. 2022;20(1):28–35. doi: 10.15584/ejcem.2022.1.4

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