Łukasz Ożóg
David Aebisher
Methods of singlet oxygen generation and detection for understanding photodynamic processes
Łukasz Ożóg
David Aebisher
Department of Photomedicine and Physical Chemistry, Medical College of Rzeszów University, Rzeszów, Poland
Department of Photomedicine and Physical Chemistry, Medical College of Rzeszów University, Rzeszów, Poland
Received: 30 June 2018 / Accepted: 5 August 2018 / Published: 30 September 2018
Abstract
Introduction. Photodynamic therapy (PDT) is a clinically approved therapeutic procedure that exerts selective cytotoxic activity toward malignant cells.
Aim. Our goal is to present the PDT procedure which involves administration of a photosensitizing agent followed by irradiation at a wavelength corresponding to the absorbance band of the photosensitizer and energy transfer to ground state oxygen to generate cytotoxic singlet oxygen
Material and methods. Analysis of literature.
Results. In this paper we described the basics of PDT and lifetime of singlet oxygen in different media.
Cite
Ożog Ł, Aebisher D. Methods of singlet oxygen generation and detection for understanding photodynamic processes. Eur J Clin Exp Med. 2018;16(3):228–232. doi: 10.15584/ejcem.2018.3.9
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