Artur Słomka
Paulina Giemza-Kucharska
Ewa Żekanowska
Piotr Korbal
Gestational diabetes mellitus has no affect on prohepcidin and other iron status parameters in infants
Artur Słomka
Paulina Giemza-Kucharska
Ewa Żekanowska
Piotr Korbal
Zakład Zaburzeń Hemostazy Katedry Patofizjologii Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Polska
Katedra Patofizjologii, Collegium Medicum UMK w Bydgoszczy, Polska
Katedra Patofizjologii, Collegium Medicum UMK w Bydgoszczy, Polska
Department of Neonatology and Neonatal Intensive Care, Jan Biziel University Hospital No 2, Bydgoszcz, Poland
Abstract
Background: Hepcidin is a major iron regulatory protein. The aim of this pilot study was to determine hepcidin precursor – prohepcidin and iron metabolism parameters in serum cord blood of infants delivered by gestational diabetes mellitus mothers (GDM).
Materials and methods: The study group comprised 12 infants delivered by women diagnosed with GDM. The control group consisted of 18 full-term healthy infants. In the serum cord blood were measured: prohepcidin, ferritin and soluble transferrin receptor (sTfR).
Results: There are no significant differences in prohepcidin, ferritin and sTfR concentration in serum cord blood between infants delivered by GDM mothers and healthy infants.
Conclusion: Gestational diabetes mellitus has no affect on prohepcidin and other iron status parameters in infants.
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